Advancing our understanding of RNA biology in human diseases through computational and experimental approaches
Learn MoreHuman diseases such as cancer are intrinsically entangled with complexity. The discovery of effective cures requires dealing with this complexity and greatly benefits from the development of high-resolution methods of investigation: genome-wide, multi-modal, single cell, spatially resolved. Understanding human diseases at single-cell resolution within their architectural context is a scientific challenge requiring dedicated computational analysis dealing with the volume and heterogeneity of the data.
Study human disease by single-cell and spatial omics to understand the molecular architecture of gene expression with unprecedented resolution.
Chart RNA modifications, structures and interactions in health and disease using next-generation sequencing techniques.
Develop computational methods for high-resolution analysis, integration and visualization of multi-omics data.
Follow translation dynamics using ribosome profiling and proteomics to monitor regulation in health and disease.
CIBIO Department, Via Sommarive 9
38123 Povo (TN) Italy